Thursday, September 28, 2017

Rosy Periwinkle, Vinca rosea

I grow this herb at my farm in Deming NM, and the product is fresh and safe.


                                  **************************

From Wikimedia:

The rosy periwinkle case dates from the 1950s. The rosy periwinkle, while native to Madagascar (Vinca rosea), had been widely introduced into other tropical countries around the world well before the discovery of vincristine. This meant that researchers could obtain local knowledge from one country and plant samples from another. The use of the plant as a cure for diabetes was the original stimulus for research. Effectiveness in the treatment of both Hodgkin's Disease and leukemia were discovered instead.[8] Different countries are reported as having acquired different beliefs about the medical properties of the plant.[9] The Hodgkin's lymphoma chemotherapeutic drug vinblastine is derivable from the rosy periwinkle.[10]

                         *********************

     Though this plant is called by many different names (See end of wiki article below), this is a famous plant worldwide because it is highly beneficial.  Possessing in excess of 400 alkoloids, the Rosy Periwinkle (Vinca rosea) was initially found in Madagascar, but has since been spread far and wide.  Considered tropical, it is common all over the planet now.

     The Rosy Periwinkle is admired everywhere as a ground cover in landscaped gardens and yards, but its medicinal qualities, though reltively unknown, are nothing short of amazing.  Initially used as a tea by various native peoples as a cure for diabetes, it has since been found to be effective in the treatment of Hodgkins disease, testicular cancer, certain drug resistant cancer tumors, and leukemia. 

     It has also been used by some herb enthusiasts as a daily supplement to improve blood supply to the brain, thereby providing greater nutrients to the brain in the process.  It is also a serotonin booster.

     This plant has been studied pharmacologically in a very extensive way.  Some of the pharmaceutical drugs developed from it consist of (But are not limited to) Vinculin (A treatment for diabetes), vinpocetine, Vinblastine, Vincristine, Velban and Oncovin.

    There are no known toxic effects from use of this plant, though cancer patients should refrain from using the Rosy Periwinkle or any of its extracts with St. Johns Wort.

     In double blind studies this plant and its derivatives have been very successful in treating vascular dementia caused by plaque build up in the arteries which supply the brain with oxygen and nutrients,  The plant has well known vascular dilating, blood thinnning, and memory enhancing properties.

     People of India use the leaf for treating external wounds.  It is also used around the world to relieve high blood pressure, relieve anxiety, and it is used externally for nose bleeds and mouth/throat disorders.

                      *****************************

     Here is the wikipedia article on the plant:


     Catharanthus roseus
From Wikipedia, the free encyclopedia
Madagascar rosy periwinkle
Catharanthus roseus
Scientific classification
Kingdom:     Plantae
(unranked):     Angiosperms
(unranked):     Eudicots
(unranked):     Asterids
Order:     Gentianales
Family:     Apocynaceae
Genus:     Catharanthus
Species:     C. roseus
Binomial name
Catharanthus roseus
(L.) G.Don, 1837
Synonyms

    Vinca rosea (basionym)
    Ammocallis rosea
    Lochnera rosea

    Wikimedia Commons has media related to Catharanthus roseus.
A Catharanthus Roseus flower in Hyderabad, India

Catharanthus roseus, commonly known as the Madagascar periwinkle, rosy periwinkle or teresita as it is usually named in the southern part of Mexico, specifically in Champotón, Campeche and Mérida,[1] is a species of flowering plant in the dogbane family Apocynaceae. It is native and endemic to Madagascar, but grown elsewhere as an ornamental and medicinal plant, a source of the drugs vincristine and vinblastine, used to treat cancer. Other English names include Vinca, Cape periwinkle, rose periwinkle, rosy periwinkle, and "old-maid".[2][3] It was formerly included in the genus Vinca as Vinca rosea.

Contents

    1 Synonyms
    2 Description
    3 Cultivation and uses
    4 Chemical constituents
    5 Other names
    6 Gallery
    7 References
    8 External links

Synonyms

Two varieties are recognized

    Catharanthus roseus var. roseus

    Synonymy for this variety

        Catharanthus roseus var. angustus Steenis ex Bakhuizen f.[4]
        Catharanthus roseus var. albus G.Don[5]
        Catharanthus roseus var. occellatus G.Don[5]
        Catharanthus roseus var. nanus Markgr.[6]
        Lochnera rosea f. alba (G.Don) Woodson[7]
        Lochnera rosea var. ocellata (G.Don) Woodson

    Catharanthus roseus var. angustus (Steenis) Bakh. f.[8]

    Synonymy for this variety

        Catharanthus roseus var. nanus Markgr.[9]
        Lochnera rosea var. angusta Steenis[10]

Description

It is an evergreen subshrub or herbaceous plant growing 1 m tall. The leaves are oval to oblong, 2.5–9 cm long and 1–3.5 cm broad, glossy green, hairless, with a pale midrib and a short petiole 1–1.8 cm long; they are arranged in opposite pairs. The flowers are white to dark pink with a darker red centre, with a basal tube 2.5–3 cm long and a corolla 2–5 cm diameter with five petal-like lobes. The fruit is a pair of follicles 2–4 cm long and 3 mm broad.[11][12][13][14]

In the wild, it is an endangered plant; the main cause of decline is habitat destruction by slash and burn agriculture.[15] It is also however widely cultivated and is naturalised in subtropical and tropical areas of the world.[11] It is so well adapted to growth in Australia, that it is listed as a noxious weed in Western Australia and the Australian Capital Territory,[16] and also in parts of eastern Queensland.[17]
Pale Pink with Red Centre Cultivar
Cultivation and uses

The species has long been cultivated for herbal medicine and as an ornamental plant. In Ayurveda (Indian traditional medicine) the extracts of its roots and shoots, though poisonous, are used against several diseases. In traditional Chinese medicine, extracts from it have been used against numerous diseases, including diabetes, malaria, and Hodgkin's lymphoma.[12] Many of the vinca alkaloids were first isolated from Catharanthus roseus,,[18] including vinblastine and vincristine used in the treatment of leukemia[15] and Hodgkin's lymphoma.[12]
A Periwinkle shrub in Hyderabad, Pakistan

This conflict between historical indigenous use, and recent patents on C.roseus-derived drugs by western pharmaceutical companies, without compensation, has led to accusations of biopiracy.[19]

C. roseus can be extremely toxic if consumed orally by humans, and is cited (under its synonym Vinca rosea) in the Louisiana State Act 159.

As an ornamental plant, it is appreciated for its hardiness in dry and nutritionally deficient conditions, popular in subtropical gardens where temperatures never fall below 5 °C to 7 °C, and as a warm-season bedding plant in temperate gardens. It is noted for its long flowering period, throughout the year in tropical conditions, and from spring to late autumn, in warm temperate climates. Full sun and well-drained soil are preferred. Numerous cultivars have been selected, for variation in flower colour (white, mauve, peach, scarlet and reddish-orange), and also for tolerance of cooler growing conditions in temperate regions. Notable cultivars include 'Albus' (white flowers), 'Grape Cooler' (rose-pink; cool-tolerant), the Ocellatus Group (various colours), and 'Peppermint Cooler' (white with a red centre; cool-tolerant).[11]

C. roseus is used in plant pathology as an experimental host for phytoplasmas.[20] This is because it is easy to infect with a large majority of phytoplasmas, and also often has very distinctive symptoms such as phyllody and significantly reduced leaf size.[21]
Chemical constituents

Vinblastine and vincristine, chemotherapy medications used to treat several types of cancers, are found in the plant[22][23][24][25] and are biosynthesised from the coupling of the alkaloids catharanthine and vindoline.[26] The newer semi-synthetic chemotherapeutic agent vinorelbine, used in the treatment of non-small-cell lung cancer,[24][27] can be prepared either from vindoline and catharanthine[24][28] or from the vinca alkaloid leurosine,[29] in both cases via anhydrovinblastine.[28]

Rosinidin is an anthocyanidin pigment found in the flowers of C. roseus.[30]
Other names
    This section does not cite any sources. Please help improve this section by adding citations to reliable sources. Unsourced material may be challenged and removed. (June 2016) (Learn how and when to remove this template message)

Botanical Names Vs Common Names can be confusing. There are many common names for this periwinkle or Vinca[31].C. roseus is known as boa-noite ("good night") and maria-sem-vergonha ("shameless maria", name shared with Impatiens and Thunbergia alata) in Portuguese (American), vinca-de-madagáscar, vinca-de-gato ("cats' vinca"), vinca-branca (white vinca), vinca or boa-noite in Portuguese (European), vinca del Cabo, vinca rosa ("pink vinca") or vinca rosada ("roseous vinca") in Spanish, putica ("little whore") in Venezuela, "İzmir Güzeli" in Turkish (meaning Smyrna beauty) indicating the city that has the best climate conditions for it to flourish in Turkey, and "Dhafnaki" [in Greek Language Δαφνάκι] (meaning little Daphne) in Greece and Cyprus. It is also called Nithya Kalyani (நித்ய கல்யாணி) and Sudukaatu Mallikai in Tamil Nadu. It is called Nayantara (নযনতারা) ("eyeball") in Bengali.

No comments:

Post a Comment